expression of iNOS and its control in human intrauterine tissues at term.
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expression of iNOS and its control in human intrauterine tissues at term.

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Published by University of Wolverhampton in Wolverhampton .
Written in English

Book details:

Edition Notes

Dissertation (Ph.D.) - University of Wolverhampton 2001.

ID Numbers
Open LibraryOL19052101M

Download expression of iNOS and its control in human intrauterine tissues at term.


  An increased mRNA expression of iNOS has been registered in cervical tissue at term labour compared to the non-pregnant state. A newly published study has shown that the nitric oxide metabolite levels in cervical fluid in women going beyond term was 4,5 times (p by:   iNOS is stimulated in a proinflammatory or an inflammatory condition and produces a temporary excess of NO. iNOS expression has been detected in placental tissues (within the placenta, iNOS Cited by: Abstract: The expression of the inducible nitric oxide synthase (iNOS) is one of the direct consequences of an inflammatory process. Early studies have focused on the potential toxicity of the ensuing high-output NO-synthesis serving as a means to eliminate pathogens or tumor cells but also contributing to local tissue destruction during chronic inflammation.   Effect of intrauterine undernutrition on mRNA expression for eNOS and iNOS in the adult offspring mRNA expression for eNOS was lower in R males than in C males at 14 weeks of age, whereas no statistical differences were observed between the R and C EF females groups (Fig. 6).Cited by:

rna and protein expression summary i Below is an overview of RNA and protein expression data generated in the Human Protein Atlas project. Analyzed tissues are divided into color-coded groups according to which functional features they have in common. – Nervous system tissues • Mesoderm becomes: – Muscular tissues – Connective tissues – Urogenital system – Lining of body cavities and blood vessels • Endoderm becomes: – Epithelia of most internal surfaces – Some glands (e.g. thyroid, pancreas, liver)File Size: 1MB. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium - calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS).BRENDA: BRENDA entry. the human proteome; the tissue atlas the cell atlas the pathology atlas the brain atlas the blood atlas the metabolic atlas protein classes protein evidence news; news articles events press room learn; dictionary methods educational videos the project; introduction organization publications publication data .

In the physiology of placental blood circulation, nitric oxide (NO) synthases seem to play important roles, although their expression in pathological placentas and their role is still unclear. In a Cited by: Purchase Epigenetics in Human Disease - 1st Edition. Print Book & E-Book. ISBN , A Role of iNOS Gene Expression in the Anti-inflammatory and Tissue Protective Mechanisms of nm Pulse. A role of iNOS gene expression in the anti-inflammatory and tissue protective mechanisms of nm pulsed laser Size: KB. Inducible nitric oxide synthase (iNOS) gene expression and NO production can be stimulated in many cell types with suitable agents such as bacterial lipopolysaccharides, cytokines, growth factors and other compounds. Many signaling pathways are involved in the regulation of iNOS expression, such as IKK-IκB-NF-κB, JAK-STATs, PI3K-Akt, MAPKs, as well as the ubiquitin-proteasome degradation .